OUDE Hypoforum

THYROID HORMONES AND MITOCHONDRIA
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It's been assumed that thyroid hormones target the mitochondria as part

of their role in energy metabolism, but the relationship between

thyroid and metabolism has not been completely clear. In this research,

scientists exploring this issue reported that two iodothyronines have

been identified as having an effect on the actions of thyroid hormones

on energy metabolism: triiodothyronine (T3) and diiodothyronine (T2).

Both of these components have significant effects on basal metabolic

rate. T3 acts on the nucleus, and T2 directly influences mitochondrial

energy.

Note from Mary: The effects of T3 and T2 - both of which are components

of natural desiccated thyroid, but not of synthetic T4-only

levothyroxine preparations like Synthroid or Levoxyl - may explain why

the natural drugs work better for some patients.

Source: Biosci Rep 2002 Feb;22(1):17-32

---> en ook dit veel uitgebreidere artikel:::

http://journals.endocrinology.org/jme/019/0137/0190137.pdf